Monitoring blood coagulation is a vital problem within the surgeries and BloodVitals SPO2 the therapy of cardiovascular diseases. In this work, BloodVitals insights we reported a novel strategy for the blood coagulation monitoring primarily based on a micro-electromechanical film bulk acoustic resonator. The resonator was excited by a lateral electric field and operated below the shear mode with a frequency of 1.9GHz. Based on the obvious step-ladder curves of the frequency response to the change of blood viscoelasticity, the coagulation time (prothrombin time) and the coagulation kinetics had been measured with the sample consumption of solely 1μl. The procoagulant exercise of thromboplastin and BloodVitals device the anticoagulant impact of heparin on the blood coagulation course of had been illustrated exemplarily. 0.99969 and a consistency with the coefficient of variation less than 5% compared with the industrial coagulometer. The proposed film bulk acoustic sensor, which has the advantages of small size, gentle weight, low value, simple operation and little pattern consumption, is a promising device for miniaturized, on-line and automated analytical system for routine diagnostics of hemostatic standing and personal well being monitoring.

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